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KOENZIM Q10
Coenzyme Q10, called “Ubiquinone”, is found in all body cells of humans, animals and plants and chemically has a ring-shaped quinone structure.
Coenzyme Q10 is particularly important in mitochondria. Coenzyme Q10, a vitamin-like, endogenous compound, is essential for energy production in mitochondria. In mitochondria, with the help of oxygen, energy in the form of adenosine triphosphate (ATP), the body’s own “energy currency”, is formed from carbohydrates, fats and proteins in food. This energy is basically the fuel for our cells.
Coenzyme Q10 performs vital functions in our body (1,2).
1- The number of mitochondria in a body cell can vary greatly depending on the tissue and cell type.
Cells that require a lot of energy contain more mitochondria.
2- Coenzyme Q10 plays an important role in energy metabolism and is essential for a robust immune system. 97% of our energy-providing metabolic processes depend on the presence of Coenzyme Q10 + NADH.
3- Coenzyme Q10 and NADH play an important role in the formation of cellular ATP energy.
NADH + Q10 means: Protection, power and performance = full energy!
ATP is stored in the body in very small quantities and therefore needs to be constantly replenished. The amount of ATP a person consumes each day roughly corresponds to their body weight! For example, the cells of a person weighing 70 kg consume about 70 kg of ATP every day.
Conventional powdered Coenzyme Q10 (ubiquinone) in a capsule is very poorly (5 to 8%) absorbed by the intestine. This is related to its crystalline structure, molecular size and properties as a fat-soluble substance.
Coenzyme Q10 can be absorbed by the body much better if it is packed in a natural “shell”. Special ring-shaped carbohydrates derived from plant starch can be used for this purpose.
Why we need coenzyme Q10 (3, 4, 5, 6)
1- It plays an important role in providing energy to body cells.
2- It is consumed in the lungs, liver and heart, which need energy more.
3- The more mitochondria a cell has, the more Q10 it contains.
4- Protects cells from free radical attacks.
5- It slows down the aging process.
6- Increases fat burning.
7- Strengthens the immune system.
8- Supports cell health and repair.
9- Enhances the anti-inflammatory effect.
10- Strengthens the heart and circulation.
Coenzyme Q10 deficiency may occur due to various factors (7,8):
– Stress
– Heavy and competitive sports
– Unhealthy diet – Fat-poor diet
– Smoking
– Excessive coffee consumption
– Alcohol consumption
– Poor quality sleep
– Use of certain medications that can reduce the amount of Q10 produced by the body, such as cholesterol-lowering drugs (statins)
– Inadequate intake of vitamins and minerals
– Overcooking of foods and long-term storage of cooked foods
In addition, the requirement for Coenzyme Q10 increases in some cases (9):
– Increased physical exertion
– Excessive exercise
– Vegetarian and vegan diet
– Pregnancy and lactation
– Advanced age
– Chronic diseases, metabolic disorders or medication use
REFERENCES
- Bonakdar RA, Guarneri E. Coenzyme Q10. Scripps Center for Integrative Medicine, La Jolla, California Am Fam Physician. 2005 Sep 15;72(6):1065-1070. PMID: 16190504
- Raizner AE. Coenzyme Q10. Methodist Debakey Cardiovasc J. 2019 Jul-Sep; 15(3): 185-191. PMID: 31687097. doi: 10.14797/mdcj-15-3-185
- Maraver JG, Cordero MD, Avila MO. Clinical applications of coenzyme Q10. Front Biosci (Landmark Ed). 2014 Jan 1;19:619-33. PMID: 24389208. doi: 10.2741/4231.
- Al-Hasso S. Coenzyme Q10: A Review. Hospital Pharmacy, 36(1), 51-66 (2001). doi:10.1177/001857870103600107
- Hernández-Camacho JD, Bernier M, López-Lluch G. Coenzyme Q10 Supplementation in Aging and Disease. Front. Physiol., 05 February 2018 | https://doi.org/10.3389/fphys.2018.00044
- DiNicolantonio JJ, Bhutani J, McCarty MF. Coenzyme Q10 for the treatment of heart failure: a review of the literature. Open Heart 2015;2:e000326. doi:10.1136/openhrt-2015- 000326. doi:10.1136/openhrt-2015-000326
- María Alcázar-Fabra M, Trevisson E, Brea-Calvo G. Clinical syndromes associated with Coenzyme Q10 deficiency. Essays Biochem (2018) 62 (3): 377–398. https://doi.org/10.1042/EBC20170107
- Potgieter M, Pretorius E, Pepper MS. Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation. Nutrition Reviews, Volume 71, Issue 3, March 1, 2013, Pages 180 188, https://doi.org/10.1111/nure.12011
- Guest PC. Reviews on Biomarker Studies in Aging and Anti-Aging Research. Advances in Experimental Medicine and Biology(2019). doi:10.1007/978-3-030-25650-0